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You are here: Home / Archives for Osteoporosis

Bone Health Improved Even by a Little Physical Activity

As little as 120 minutes of walking or other exercise was associated with biomarkers of bone strength in premenopausal women, according to the results of a cross-sectional study. An 8-week physical activity intervention program significantly increased biomarkers of bone strength compared with sedentary control patients.

Mohammed-Salleh M. Ardawi, PhD, FRCPath, from King Abdulaziz University Hospital in Jeddah, Saudi Arabia, and colleagues report their results in an article published online August 3 in the Journal of Clinical Endocrinology and Metabolism.

“Physical activity is good for bone health and results in lowering sclerostin, a known inhibitor of bone formation and enhancing IGF-1 levels, a positive effector on bone health,” Dr. Ardawi said in a news release. “We also found physical activity training that enhances mechanical loading in combination with anabolic therapeutic agents will have added positive effect on bone health, particularly bone formation.”… [Continue Reading]

Filed Under: Osteoporosis Tagged With: bone health, osteoporosis, sclerostin

The Role of FRAX in Osteoporosis

Osteoporosis is a systemic skeletal disorder that remains underdiagnosed and undertreated, although we now have a better understanding of the disease and better tools to manage it. Osteoporosis is the most common metabolic bone disease, affecting 10 million Americans, with an additional 33.6 million having reduced bone mineral density (BMD) of the hip.1 One in 2 Caucasian women and 1 in 5 men will experience an osteoporosis­related fracture over their lifetime, responsible for more than 1.5 million fractures every year.

When an osteoporosis­related fracture occurs, it can have a debilitating effect on patients. In women with hip fractures related to osteoporosis, less than 50% will regain their ability to participate in activities of daily living. Nearly 20% will require long­term care in a nursing home. Hip fractures result in a substantial incidence of mortality, with about 20% to 24% of patients dying within the first year after fracture.1
Because osteoporosis occurs without signs and symptoms until a fracture occurs, clinicians should attempt to identify those patients at risk for fractures in order to initiate lifestyle changes and offer medication.… [Continue Reading]

Filed Under: Osteoporosis

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